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These findings come from controlled laboratory models and describe physical chemistry, not biological activity

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The presence of multiple amide carbonyl groups and nitrogen atoms contributes to polar surface area

Comment: A commenter requested that we remove the Multiple Procedure Payment Reduction (MPPR) assignment from CPT code 64596 (insertion of neurostimulator electrode array, peripheral nerve) and reassign it from Y to N status in ASC Addendum AA for CY 2026, stating that the current multi-procedure discount results in inequitable payment access since bilateral implantation or multiple nerve targeting requires separate StimRouter devices with individual incision and tunneling procedures