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2018;2(2):CD010585

Resistance to therapy in BRCA2 mutant cells due to loss of the nucleosome remodeling factor CHD4

Dysregulation of autophagy in PTECs could lead to morphological alterations including hypertrophy, hyperplasia and EMT which further lead to renal structural changes such as renal hypertrophy, tissue injury and interstitial fibrosis (101, 102)

Vitamin C works towards the growth of healthy cells, the elasticity of the skin and the prevention of fine lines and wrinkles

Disulfiram targets cancer stem-like properties and the HER2/Akt signaling pathway in HER2-positive breast cancer

In a preclinical melanoma model, CB-839 significantly improved the therapeutic efficacy of adoptive T-cell therapy and immune checkpoint inhibitors (anti-PD1 and anti-CTLA4), triggering a superior immune response (Varghese et al., 2021)