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The following day under the same anaesthetic conditions, mice were placed onto a heated platform in a supine position with paws taped down onto pads for heart rate monitoring

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The coarse model grid biases can be seen in Fig

In a double-blind study of n=16 chronic insomniac patients, intravenous DSIP at 25 nmol/kg over 3 nights was associated with higher sleep efficiency and shorter sleep latency (the time it takes to fall asleep) compared with placebo, but the effects were described as weak [4]