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Another study examined pathophysiological changes in a mouse model by exposing it to high linear energy transfer (LET) radiation

You may qualify if you meet the following criteria: Healthy Male & Female or non-childbearing volunteers Aged 18-55 inclusive at screening BMI 18-32 at screening A non-smoker Must be available for 1 inpatient period of 5 days/ 4 nights with 1 follow-up visit 7 days after last dose

J Natl Cancer Inst (2009) 101(7):51932

Huth, Teilah K

Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity