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Deferoxamine ameliorates hepatosteatosis via several mechanisms in ob/ob mice

Injection site reactions (mild redness, transient swelling) are the most common, typically resolving within 24 hours

NAC application elevated the protein levels of p35, the neuronal-specific activator of Cdk5, thereby enhancing Cdk5 activity

Concurrently, a spectrum of inflammatory mediatorsincluding cytokines, chemokines, and proteasesis released, collectively establishing a persistent pro-inflammatory microenvironment that sustains disease progression ( In recent years, targeted studies have further unraveled the complex regulatory mechanisms of chronic inflammation in COPD, spanning molecular pathways, cellular effects, animal models, microecological balance, and immune defense

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