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It consumes NAD+ (a critical coenzyme for cellular energy and DNA repair) and facilitates fat storage

When these receptors interact with a circulating platelet-activating molecule called adenosine diphosphate (ADP), they upregulate expression of a protein complex involved in platelet aggregation

The drug itself is coded separately using HCPCS code J3490 (unclassified drugs) with the appropriate NDC number for the specific tirzepatide product (Mounjaro or Zepbound)

doi: 10.1021/jo0706832

Semaglutide and tirzepatide are FDA-approved and have demonstrated 15 to 22 percent total body weight loss in large clinical trials

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