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Specifically, the nucleic acids and polypeptides according to the invention may be used as targets for the identification of small molecules that modulate or inhibit diseases associated with the protein families listed in Table A

(C) Western blot to verify specific siRNA knockdown of GCLm, GR, and GSS

This preclinical data provides an excellent base for human safety and efficacy trials [25]

Maeda Y, Loughrey A, Earle JA, Millar BC, Rao JR, Kearns A,

Yamatani K, Carter BZ, Konopleva M, Tabe Y, Andreeff M

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