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We showed that the GCLC mRNA expression level was downregulated by ACTL6A KD and was upregulated when ACTL6A was overexpressed, but the GCLM expression was not changed (Supplementary Fig 5a, b)

In this way, it seems that although the three human isoforms of superoxide dismutase (SOD), copper/zinc (Cu/Zn)-SOD, manganese (Mn)-SOD, and extracellular (EC)-SOD, form the primary endogenous defense against oxidative stress, their expression levels and cellular localization in IBD mucosa might be controversial

Solids 60 , 965968 (1999)

An adhI mutant strain of R

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