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We conclude that while recent evidence suggests that the effect of hypoxia on ROS production is highly dependent on the cell type and the duration of exposure, efforts should be made to conduct experiments under carefully controlled, physiological microenvironmental conditions in order to rule out potential artifacts and improve reproducibility in research

Oxygen and carbon dioxide were measured in the sealed treadmill chamber every 15 s

Autophagy (Greek for self-eating), a lysosomal degradation pathway, was first termed by Christian de Duve, who also discovered the lysosome, where intracellular protein degradation occurs [38]

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They found that probiotic supplementation significantly reduced the frequency of migraine attacks, the frequency of drug use, digestive problems, zonulin levels, and Hs-CRP levels (213)

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