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When used concurrently with phlebotomy, high dose erythropoietin (150 U/kg three times per week) has been reported to be more efficacious than low dose (50 U/kg two to three times weekly) [70] Interestingly, successful anecdotes of erythropoietin monotherapy (150 U/kg three times weekly) have been reported in hemodialysis-related PCT [1012, 73]

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It can inhibit the activation of PI3K/AKT signaling through the inverse regulation of IGF-1 expression and ultimately suppress the tumorigenesis of cervical cancer cells (80)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 251.Xu J., Zhang W., Cui W., Shi B., Wang H