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Description

In prokaryotes, glutathione maintains the proper oxidation states of protein thiols and protects cells from damage under abnormal conditions such as low pH, chlorine compounds, oxidative and osmotic stresses 8

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Prior studies have reported that active metabolites of fenofibrate can regulate metabolism, fatty acid synthesis, and other cellular processes disrupted by viral infections

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Homologous 1-Cys proteins are widely distributed throughout all kingdoms, and they have been described in archaea, bacteria, parasites, yeast, insects, mollusks, amphibians, birds and other orders (130) (Table I)

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Studies on autophagy and various neurodegenerative diseases are summarized in Table 1

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10.1016/j.neuro.2013.01.002 219 RothsteinJ

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The most important predictor is whether the source of exposure has been fully addressed recovery cannot complete while exposure continues

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