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Consequently, some aspects of MCUR1 deficiency observed in fibroblasts may underestimate the true impact of the variant in the primarily affected tissue

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PromratKKleinerDENiemeierHMJackvonyEKearnsMWandsJRet al

Patients already receiving statin therapy were maintained on an equivalent dose of simvastatin (10 to 20 mg/d) up to the study end, whereas patients who were not on statin therapy started simvastatin 10 or 20 mg/d as deemed clinically appropriate

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Dyslipidemia is independently associated with AF incidence (Guan et al., 2020), and lipid metabolism related proteins serve as a potential AF biomarker (such as LDL, VLDL, HDL, and FABP3) (Golaszewska et al., 2019)