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It is currently believed that AhR signaling pathway plays a key role in inflammatory diseases and autoimmune diseases (80)

This material is intended for qualified research professionals and institutions only

This approach would capitalize both on our understanding of circadian pathophysiological pathways in asthma, and existing redox-targeted therapeutics, whilst minimizing off-target effects associated with hormone based therapies such as melatonin

doi: 10.1016/j.cyto.2022.156107, PMID: [DOI] [PubMed] [Google Scholar] 27

Han BH, Zhou M-L, Johnson AW et al (2015) Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice