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The treatment was found to trigger SOD activity, which in turn drove hydrogen peroxide (H 2 O 2 ) production and fostered the Fenton reaction, thereby aggravating oxidative stress-induced ferroptosis by NaIO 3 (81)

2.1 Precise Control of Core Fermentation Parameters We have established optimal control ranges for key fermentation parameters, laying a solid foundation for stable, large-scale production: Carbon source concentration (glucose): 2228 g/L Magnesium ion concentration (magnesium sulfate): 2.03.0 g/L Culture temperature: 2630C Through continuous fermentation monitoring, we determined a 24-hour cycle as the optimal fermentation period