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Measurement of LDH activity Lactate Dehydrogenase (LDH) activity was measured by a standard kit (A020-2, Nanjing Jiancheng Bioengineering, China)

Most mutations (including the p.Gly376Asp) promote cytoplasmic mislocalization [20] and formation of toxic protein aggregates [21], coupled to a depletion TDP-43 in the nucleus that causes a loss of the nuclear function of the protein [22]

F 2 -IsoPs, F 2 -isoprostanes

In the human knee joint, the selenium concentration in cartilage is approximately 80 g/kg dry weight, whereas the selenium concentrations in ligament and meniscus are 270 and 307 g/kg dry weight, respectively 60,61

[DOI] [PubMed] [Google Scholar] 270.Dong L., Zhang X., Yang F., Li J., Yu X., Li Y

370 This evidence highlights the critical role of neutrophils in the pathogenesis of SLE