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The mechanism of action is due to the fact that Larazotide acts as an antagonist against zonulin, which is a protein in the small intestine that affects gut permeability

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doi: 10.1007/s12012-023-09804-7 72 RyanFBlexCNgoTDKoppMAMichalkeBVenkataramaniVet al

Many patients prefer dosing on a weekend morning so any initial side effects happen when work and obligations are minimal

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Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer's disease