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A 2022 study published in the Journal of Investigative Dermatology demonstrated that 1% GHK-Cu solutions reduced Cutibacterium acnes colony-forming units by 89.4% within 72 hours, compared to 76.2% for 5% benzoyl peroxide

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To analyze known arterial and venous markers, respectively, we used Aplnr-CreERT2 and Bmx-CreERT2 transgenic mice in combination with the Rosa26-mTmG Cre reporter 30,32,33

The therapeutic dose is approximately 300-fold below the toxic threshold according to animal studies

LR3's reduced IGFBP binding is a relative, not absolute, reduction