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As we continue to refine these approaches, it is likely that senolytic and senomorphic agents will become an integral part of clinical strategies aimed at enhancing the quality of life for aging populations and mitigating the impact of age-related disorders

For example, a 2023 RCT revealed that only a subset of adults experienced substantial alterations in gut microbiota and metabolic markers following a standardized probiotic, with responses closely associated with baseline community composition (573)