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doi: 10.1002/mc.23789 29 GyoriDLimELGrantFMSpensbergerDRoychoudhuriRShuttleworthSJet al

Although PRLMs show considerable therapeutic potential for hypertension, their clinical translation remains constrained by several challenges [123]

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Proinflammatory cytokines further stimulate ROS overproduction aggravating ARDS and lung damage causing a vicious circle between oxidative stress and cytokine storm

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Reactive oxygen species that play the greatest role in the initiation of oxidative stress include hydrogen peroxide, superoxide anion radical, and hydroxyl radical (82)