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On one hand, Nrf2 activates downstream target genes to regulate iron metabolism-related genes, reducing intracellular free iron accumulation and Fenton reaction-induced oxidative damage (126130)

In the absence of a specific antidote, early recognition, close monitoring, and judicious supportive management remain crucial

Lipid depletion observed in Hhex KO male mice results in part from activation of lipophagy in the inner zF To better understand the mechanisms by which HHEX protects the sterol content of the zF, we interrogated cholesterol ester uptake, lipid droplet catabolism, and de novo synthesis

Francis RO et al (2013b) Glucose-6-phosphate dehydrogenase deficiency in transfusion medicine: the unknown risks

Both the outer and inner segments of PR render it exceptionally susceptible to LPO and ferroptosis

Vitamin D supplementation promotes macrophages anti-mycobacterial activity in type 2 diabetes mellitus patients with low vitamin D receptor expression