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Other research has shown that higher temperatures can interfere with metabolic signaling pathways of the bacteria thereby killing the bacteria without damaging the surrounding healthy tissues (Zhang et al., 2019

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Nature 457 , 413420 (2009)

Due to nanomaterials biocompatibility, high loading capacity, and stimuli-responsive drug release properties, stimuli-responsive nanoparticles have garnered the attention of scientific community and widely utilized in the biomedical applications, particularly in drug delivery

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In order to preserve its effectiveness, the skin is sustained endogenously (protected from within) through an oxidant-antioxidant balance