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The parents of an individual with an autosomal recessive disorder each carry one copy of the defective gene, but usually are not affected by the disorder

Urology 1990

The intricate balance between energy supply and demand in neurons, astrocytes, and microglia, and their dynamic interactions under both normal and pathological conditions, underscores the complexity of maintaining brain health

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* MCT: medium-chain triglycerides are absorbed into the portal vein, thus by-passing the need for digestion, micelle formation and lymphatic transport which are essential for long-chain triglyceride assimilation

The hepatotoxicity of PZA is dose-dependent, especially at doses above 40 mg/kg, and correlates with its hepatic metabolism, suggesting a direct toxic effect rather than a hypersensitive or immune-mediated mechanism