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MM was involved in conducting the phase 1 and 2 portions of this study, in performing the plasma L-citrulline and L-arginine analyses in phase 3, and was involved in manuscript preparation

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doi: 10.1186/s13024-020-00378-4 53 BurgosJ

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Analysis of over 11,000 participants in the SUSTAIN and PIONEER trials revealed that gastrointestinal disorders were the predominant adverse effects, occurring in approximately 39-42% of semaglutide users compared to 22-25% of those receiving comparators

Gpx4 Regulates Invariant NKT Cell Homeostasis and Function by Preventing Lipid Peroxidation and Ferroptosis