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Another study showed that DFO could suppress excessive collagenase-mediated type II collagen cleavage and protease, production of cytokine, and COL10A1 expression while upregulating adenosine monophosphate-activated protein kinase and Krebs cycle genes in human osteoarthritic cartilage [125]

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Caution should be observed with administration of warfarin sodium to elderly patients in any situation or physical condition where added risk of hemorrhage is present

10.1016/j.abb.2012.04.014 Vido K, Diemer H, Van Dorsselaer A, Leize E, Juillard V, Gruss A, Gaudu P: Roles of thioredoxin reductase during the aerobic life of Lactococcus lactis

doi: 10.1111/j.1398-9995.1990.tb00528.x

Room temperature storage exposes peptides to atmospheric oxygen, and higher temperatures increase oxidation rates