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We also demonstrated that DPI significantly increases mitochondrial ROS production in MNA cells, but not in non-MNA cells, indicating a MYCN-dependent effect (16)

Conversely, it is easy to have a deficiency, especially with restrictive diets

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Comorbidities like type 2 diabetes and metabolic syndrome a cluster of metabolic disorders that includes obesity, dyslipidemia, hypertension, and insulin resistance, leading to chronic systemic inflammation