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doi:10.1111/j.1939-1676.2011.0732.x 5

Injecting cold liquid into a cold vial creates unnecessary condensation and thermal stress

This happens because the active ingredient, guaifenesin, can sometimes irritate the lining of your stomach

Xu, C., Sun, L., Ren, F., Huang, P., Tian, Z., Cui, J., Zhang, W., Wang, S., Zhang, K., He, L., Zhang, W., Zhang, C., Hao, Q., Zhang, Y., Li, M., & Li, W