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While face taping for wrinkles can smooth the skin for a night, only clinically proven options like collagen induction therapy, microneedling, and neurotoxins deliver visible, long-term improvement

Applications in Animal Aging Models Animal aging models (such as naturally aged mice, D-galactose-induced aging mice, SAMP8 accelerated senescence mice, etc.) are core carriers for simulating human aging and verifying the efficacy of anti-aging drugs

The research is conflicting, and no human studies have definitively established either benefit or harm in cancer patients

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Conclusion and perspectives In this review, we briefly summarized the pathophysiology of IBD and current clinical management strategies

10.7150/ijbs.35440 44 ZouM