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(2) changes in the serum levels of ALT and aspartate transaminase (AST)

Understanding titration: Why you cant start at a higher dose Titration is the process of starting a medication at a low dose and gradually increasing the dose over time

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They will also set an upper limit on the total weekly dose (for example, some experts recommend not exceeding approximately 300 mg per week in subcutaneous dosing without further evaluation) to minimize any risk of adverse effects