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A third widely-cited paper (McCoy 2013, PMID 23055539) the source of the often-repeated "seven orders of magnitude more potent than BDNF" line carries a 2021 Expression of Concern

For proteomic analysis, detergent in final washes was sequentially removed, and samples processed immediately

Activating transcription factor 4 (ATF4) can directly bind to the promoters of both PHGDH and PSAT1 and promote their expression under amino acid deprivation and hypoxia (Ye et al., 2012

Gut microbiota-derived autoinducer-2 regulates lung inflammation through the gut-lung axis