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Therefore, the well-thought-out design of nanomaterials for use in autophagy modulation strategies may provide multifunctional capabilities and spatiotemporal control over immune cells, ultimately enhancing anti-cancer activities while ensuring improved safety profiles

Meyer SC, O'Meara A, Buser AS, Tichelli A, Passweg JR, Stern M

Gandhi, R., Gillespie, P

This leads to a state of frustrated phagocytosis and the release of damaging proteases and reactive oxygen species (ROS) that cause significant collateral damage to the host tissue without effectively clearing the bacteria, which are often protected within biofilms (Gifford and Chalmers, 2014)

[7] [8] This triple-receptor mechanism distinguishes it from existing approved agents such as semaglutide (a GLP-1 agonist) or tirzepatide (a dual GLP-1/GIP agonist)

The results showed increased anti-inflammatory Arg-1 gene expression and decreased proinflammatory markers (including TNF-, , and IL-1-6)