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Synthesis of ketone bodies may be initially increased in MASLD as a mechanism to safely manage excess triglyceridederived acetylCoA via nonoxidative disposal to limit oxidative stress, a mechanism which becomes disturbed as MASLD progresses (Post et al

High concentrations of PA in breast milk can promote cellular inflammation by inducing inflammatory responses [36]

Studies show that limiting alcohol intake helps maintain stable homocysteine levels and supports glutathione production

In liver tissue from Gclc KO mice, we observed an accumulation of glutamate but no difference in cysteine and glycine levels (Fig

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