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BDNF has been implicated in neuronal growth, differentiation, and survival, and reduced hippocampal BDNF expression may contribute to the decline in acquired memory retention and impaired cognitive functioning in rats

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Beaudry K, Langlois MJ, Montagne A, Cagnol S, Carrier JC, Rivard N

Recurrent cardiovascular risk was higher with low levels (Q1) of AT2-abs (HR = 1.86

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Increased cell death along with increased levels of ROS and mitochondrial 3-nitrotyrosine and 4-hydroxynonenal protein adducts