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Biomarker Effects Were Present Despite clinical failure, semaglutide showed biological activity: CSF biomarkers including pTau181, pTau217, and others demonstrated nominally significant reductions of approximately 10% in treated patients

doi: 10.4049/jimmunol.162.7.3749 [DOI] [PubMed] [Google Scholar] 215

Glucuronization does not occur in plants, but the corresponding formation of glucosides has been described for a couple of xenobiotics in mammalians (Kirkman et al