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Description

Discussion Although many antidepressants with different mechanisms are being used, a number of patients have not achieved appropriate therapeutic effects

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49 Moreover, administration of high doses of IL-1 fails to exacerbate APAP-induced liver injury, further suggesting a limited role of IL-1 signaling in the pathogenesis of APAP hepatotoxicity

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When liver enlargement secondary to enzyme induction exceeds an adaptive response, there is hepatotoxicity

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doi: 10.3174/ajnr.A3785

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