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A nasal spray was tried

Keap1 is a cysteine-rich protein that can be oxidized by ROS and results in conformational change, which in turn liberates NRF2

Available at fda.gov

In a randomized trial, psychobiotic Lactobacillus plantarum JYLP-326 administered for 3 weeks reduced anxiety, depression and insomnia symptoms in test-stressed college students (Zhu R