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The role of oxidative stress in vitiligo: an ppdate on its pathogenesis and therapeutic implications

Four days after the experiment, it was reported by the researchers that the murine models presented with TB-500 showed an apparent 41% increment in the re-epithelialization process (i.e., formation of new epithelial cells to resurface the wound)

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W.YogalingamP.SacherJ.RusjanP.et al (2014)

In another study, it was demonstrated that mTORC1 regulates the translation of the ATP synthase components, included ATP synthase subunit delta (ATP5D), and the transcription factor A, mitochondrial (TFAM), which promotes mitochondrial DNA replication and transcription through 4E-BPs, moreover, this was related with a higher mitochondrial activity (100)

[DOI] [PubMed] [Google Scholar] [43].Roveri A, Flohe L, Maiorino M, et al