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First isolated from human plasma in the early 1970s, it naturally occurs in blood, saliva, and urine but its concentrations decline sharply with age

Gastrointestinal permeability in celiac disease

However, this is an important demonstration of the use of natural amino acids and modification of the peptide chain to negate the challenging synthesis of chiral lipid-containing amino acids for synthesis of lipopeptides

Jaeschke, H., Xie, Y

doi: 10.1002/hep4.1857

Evensen L, Micklem DR, Blois A, Berge SV, Aarsaether N, Littlewood-Evans A, Wood J, Lorens JB: Mural cell associated VEGF is required for organotypic vessel formation