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Body weight curves from 6 weeks old to 14 weeks old, C, D

Leveraging the proximity effect enabled by this fibrillar framework, CRBN anchored on the network simultaneously mediates ubiquitination tagging of both AR and HSP90, thereby establishing a supramolecular platform for coordinated polyubiquitination and subsequent degradation of compartmentalized oncoproteins 30,33,46 (Fig

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Discussion Click chemistry, including the copper(I)-catalysed azide-alkyne cycloaddition (CuAAC) reaction, is a staple of modern synthetic chemistry and continues to provide functionality to new fields

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