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As demonstrated by certain attempts to incorporate new algorithms and construct templates for phenotype prediction, metabolomics techniques have been improving, particularly in the operation of statistical data analysis

doi: 10.1080/004982597239949

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Overall, the results of these studies show that MECP2 gene expression is necessary for normal synaptic development, the balance between the excitatory and inhibitory neurotransmission, morphology, and density of dendritic spines in the brain