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The nephrotoxic mechanisms of pCS primarily involve inducing oxidative stress through activation of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, triggering inflammatory responses, and promoting renal fibrosis (124)

Drosophila melanogaster glutamate-cysteine ligase activity is regulated by a modifier subunit with a mechanism of action similar to that of the mammalian form

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Bacteriostatic water contains a preservative (benzyl alcohol) that prevents bacterial growth, making it essential for vials that will be used multiple times