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Diabetes Care 34(9):20542060

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These results clearly indicate that interactions between the four Elp lipoprotein candidates and C1r, while still detectable, are of lower affinity compared to their interactions with C1s

Therefore, it is probable that TG2-mediated modification of GSTP1 affects the interactome of cellular GSTP1, resulting in an alteration of interactions with its binding partners

Additional experiments were conducted on the HGL5 human granulosa cell line to assess mitochondrial function and metabolic reprogramming

Our analysis showed that macrocyclic peptides were the most prevalent, accounting for more than half of the identified cyclic peptides, followed by bicyclic and polycyclic structures (see Figure 5A)