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The mitochondrial dysfunction theory of aging and the free radical theory of aging are intertwined and both would be addressed by the intracellular benefits of SS-31

Studies conducted in vitro and in animals have indicated that -tocopherol and its major metabolite, -carboxyethyl hydroxychroman (-CEHC), may play a role in protecting the body from free radical-induced damage in various conditions of oxidative stress and inflammation (reviewed in 8)

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The evidence for their effectiveness remains mixed, particularly in healthy individuals, and their long-term impact remains largely unknown