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Loss of vision: Complete loss of vision is a possible side effect from advanced diabetic retinopathy, as by this stage scar tissue and long-term weakening of the blood vessels may result in a full retinal detachment

168 Cadmium exposure leads to gut flora dysbiosis, reduced fecal BSH activity, and elevated intestinal tauro--muricholic acid levels in mice, subsequently inhibiting the intestinal FXR/FGF-15 signaling pathway, promoting hepatic bile acid synthesis, and ultimately triggering bile duct proliferation, inflammation, and injury

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T2DM patients show significantly reduced IFN-:IL-4 ratios, confirming a measurable shift away from protective Th1 immunity

Phloridzin ameliorates type 2 diabetes-induced depression in mice by mitigating oxidative stress and modulating brain-derived neurotrophic factor

Long-term therapy helps maintain optimal B12 levels, supporting continued energy production and neurological function