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Therefore, the focus of the present study is to determine whether 4-OXO-DHA can be identified as a metabolite of DHA in vivo, to examine its effects on critical molecular targets of mammary carcinogenesis in breast cancer cell lines in vitro and to elucidate the structural basis that can account for its inhibition of NF-B

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1, some participants in each arm were withdrawn due to personal reasons or poor compliance

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