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ScuderiSACasiliGBasilottaRLanzaMFilipponeARacitiGet alNLRP3 inflammasome inhibitor BAY-117082 reduces oral squamous cell carcinoma progression

Our initial attempts to hydrophobize the surface of GSH-AuNCs suggested a ligand exchange reaction to displace the glutathione molecules with a hydrophobic thiolated ligand (e.g

This can help ward off the root cause of many cognitive disorders and even improve cognitive function and memory throughout the aging process

This mechanism contributes to the progression of liver diseases such as MASLD by promoting liver cell death (apoptosis) and necrosis [96]

Lifestyle changes, especially adherence to regular physical exercise and Mediterranean diet-as reflected by reduced oxidative stress of adipocytes (as measured by plasma levels of F2-isoprostanes and carbonyls of proteins)-showed positive effects (135, 136)

Furthermore, targeting ox-LDL or its receptors (e.g., LOX-1) is being explored as a novel strategy to interrupt the oxidative-inflammatory cascade in MASLD [136, 152]