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Ishikita, H

The carboxy group of the substrate also forms hydrogen bonds with the peptide nitrogen of Ser-452 and possibly its side chain hydroxy group

It promotes the growth of keratin, which combats aging causes

dermatology 21, 513529

*Health claim ID 4141 pending European approval

The primary mechanisms through which BPC-157 promotes tissue repair include activation of the VEGFR2 signaling pathway for angiogenesis (new blood vessel formation), FAK-paxillin pathway activation that enhances cell migration to injury sites, upregulation of growth hormone receptors that amplify proliferative signals, and selective modulation of nitric oxide systems that balance beneficial vasodilation against inflammatory damage