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Although many senolytic agents, such as dasatinib and quercetin, have shown efficacy in preclinical models, their long-term effects in humans are not yet fully understood

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Interestingly, the expression of rodent PNPLA3 is highest in BAT (62, 63), and recent work demonstrates a role in regulating adipocyte lipolysis

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Molecular visualisations were further generated with commercial office productivity software, as well as with BioRender ( During the preparation of this manuscript, the authors used large language models based on the Transformer deep neural architecture (Vaswani et al, 2017), strictly in order to improve language and grammar