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Pregnane X receptor (PXR)-Mediated gene repression and cross-talk of PXR with other nuclear receptors via coactivator interactions

The subjects lost an average of 11% of their body weight over four weeks of treatment

Quelle: Parazzini, F., Vigan, P., Candiani, M., & Fedele, L

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Combined, the effects of CBD on PPAR on metabolic outcomes may differ depending on the dose and the location of the receptor, increasing adiposity and lipid accumulation, or by impacting insulin resistance