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The up conformation is a less stable state and is required in order for binding to occur [27]

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Kerbel Control of angiogenesis by the action of extrinsic angiogenesis inhibitors (antiangiogenic factors), an intrinsic endothelial cell inhibitor (vasohibin), and extrinsic stimulators of angiogenesis such as VEGF and bFGF

Thermo Fisher Scientific, Inc.) for 1 h at room temperature

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