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In conclusion, both deleterious consequences of mitochondrial impairment, i.e., restricted ATP generating capacity and ROS production, impair UPS-dependent proteolysis in neurons and are highly relevant to the pathogenesis of AD

Glutathione l hot cht c sn xut t nhin bi gan v c mt khp ni trong c th

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Furthermore, such guidelines can advance scientific research, help formulate more scientific and forward-looking treatment protocols, and enhance patient and public understanding and acceptance of the treatment options